Correction of neutropenia and hypogammaglobulinemia in X-linked hyper-IgM syndrome by allogeneic bone marrow transplantation
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چکیده
منابع مشابه
Case report Bone marrow transplantation as treatment for X-linked immunodeficiency with hyper-IgM
We report a 10-year-old boy with a severe form of immunodeficiency with hyper-IgM who underwent successful bone marrow transplantation with his HLA-matched sister as donor. Busulfan (20 mg/kg) and cyclophosphamide (200 mg/kg) were used as conditioning. The post-transplant course was uneventful. He is alive 25 months later with full hematological and immunological reconstitution. BORDIGONI, P, e...
متن کاملAllogeneic Bone Marrow Transplantation
A 1 3-yr-old male with acute myelogenous therapy. Then, 53 yr later, he developed leukemia was treated with various chemoan extramedullary relapse with a chlotherapy regimens for 3 yr and then underroma of his maxillary sinus. This case ilwent an allogeneic bone marrow translustrates the need for prolonged followup plantation. The donor marrow was sucof transplant recipients and suggests that c...
متن کاملHuman cyclic neutropenia transferred by allogeneic bone marrow grafting.
Human cyclic neutropenia shows many features in common with the animal model of cyclic neutropenia in grey collie dogs. Until now, however, evidence was lacking that cyclic neutropenia in man as in the dog is caused by a defect in a transplantable hematopoietic stem cell. A patient is presented who, while undergoing bone marrow transplantation as treatment for acute lymphoblastic leukemia in re...
متن کاملAllogeneic bone marrow transplantation for 93 patients with myelodysplastic syndrome.
We treated 93 patients with myelodysplastic syndrome using cyclophosphamide and either total body irradiation (n = 88) or busulfan (n = 5) followed by marrow transplantation. Sixty-five marrow donors were genotypically HLA-identical siblings and 28 were other family members or unrelated donors. Before transplantation all patients had either severe neutropenia or thrombocytopenia or had greater ...
متن کاملAutoimmune neutropenia after bone marrow transplantation.
Shastri and Logue, in their otherwise thorough review' of the laboratory and clinical aspects of autoimmune neutropenia, fail to mention the association between autoimmune neutropenia and bone marrow transplantation. Approximately 25 such cases have now been reported,'-" and a recent prospective study from Johns Hopkins" suggests that more than half the cases of otherwise unexplained posttransp...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 1998
ISSN: 0268-3369,1476-5365
DOI: 10.1038/sj.bmt.1701512